Polycystic Ovarian Syndrome: A Narrative Review Article on Serum Markers in Pcos

PCOD is a heterogeneous illness characterized by clinically or biochemically excess androgen, dysfunction in ovulation, and polycystic ovaries that is caused by a complicated hereditary disease.

Poly-cystic ovary syndrome (PCOS), affecting 10 to 20% of premenopausal females, is a common heterogeneous disorder depending on diagnostic criteria of high serum levels of androgen concentrations, and infertility, irregular menstruation, provided that precise diagnosis such as hyperprolactinemia and inbred adrenal hyperplasia have been debarred. In recent years, the international agreement has favored the adoption of the Rotterdam criteria for mature women's diagnosis. During pubertal development, non-uniform menses, chronic anovulatory cycles, multi-follicular ovary shape, and moderately increased blood androgen concentrations are common.

It's difficult to establish a diagnosis in adolescent females since there's a lot of overlap between typical pubertal milestones and PCOS clinical characteristics. Insulin resistance, hyperinsulinemia, and obesity are all typical symptoms of PCOS, however, they aren't diagnostic.

Impaired glucose tolerance, which leads to insulin-dependent diabetes mellitus, insulin resistance, dyslipidemia, increased blood pressure, endometrial cancer, hyperinsulinemia, obesity, alcoholic independent fatty liver, and sleep apnea are among the comorbidities linked with PCOS. Depression and poor conditions of life are also prevalent problems. Preliminary detection of PCOS in teenage females is critical.

The goal of this article is to offer a summary of serum indicators and evidence for several serum markers used to diagnose PCOS.