Spatial structure of beta-amyloid Aβ1-40 in complex with a biological membrane model

Usachev, Konstantin S. and Filippov, Andrey V. and Antzutkin, Oleg N. and Klochkov, Vladimir V. (2012) Spatial structure of beta-amyloid Aβ1-40 in complex with a biological membrane model. Advances in Alzheimer's Disease, 01 (03). pp. 22-29. ISSN 2169-2459

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Abstract

The spatial structure of beta-amyloid Aβ1-40 in complex with sodium dodecyl sulfate micelles as a model membrane system was investigated by 1H-1H two-dimensional NMR (TOCSY, NOESY) spectroscopy and molecular dynamic method calculations. On the basis of NOE and chemical shifts changes data, spatial structure of the complex beta-amyloid-model of the cell surface membrane was obtained.

Item Type: Article
Subjects: Pacific Library > Medical Science
Depositing User: Unnamed user with email support@pacificlibrary.org
Date Deposited: 14 Apr 2023 05:37
Last Modified: 15 Oct 2024 11:42
URI: http://editor.classicopenlibrary.com/id/eprint/1109

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