Evaluation of antibacterial activities of Barleria Prionitis Linn

In the present study, 1 g/ml each of Barleria prionitis leaves (BPL) and B. prionitis stem (BPS) were extracted from different solvents like petroleum ether, chloroform ethyl acetate and methanol. Ethyl acetate extract of BPL showed maximum inhibition zone on Gram positive Bacillus pumilus (9.83 mm) and methanol extract of BPS showed minimum inhibition zone on Gram negative Escherichia coli (0.16 mm). Petroleum ether extract did not show inhibition except petroleum ether extract of BPS on Gram positive B. pumilus (0.46 mm). Minimum inhibition concentration (MIC) was shown by petroleum ether extract of BPL on Gram positive B. pumilus and Gram negative Pseudomonas aeruginosa (1.0 mg/ml). Leaves and stem extract of Barleria prionitis L. showed difference in antibacterial activity.